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Indications and usage of flutamide

He, Y. H. and Kies, C. Green and black tea consumption by humans: impact on polyphenol concentrations in feces, blood and urine. Plant Foods Hum. Blackburn, H. Coffee, tea and VPB. J Chronic. Uhde TW, Boulenger JP, Jimerson DC, Post RM. Caffeine: relationship to human anxiety, plasma MHPG and cortisol. Montague, T. J. The effect of caffeine on cardiac rate, rhythm, and ventricular repolarization. Analysis of 18 normal subjects and 18 patients with primary ventricular dysrhythmia. acyclovir

How to take flutamide

Conception rates were decreased in all dosing groups. Three and one-half years after the study was initiated, median survival had been reached. Flutamide is used to treat prostate cancer. Treatment with Flutamide capsules and the goserelin acetate implant should start 8 weeks prior to initiating radiation therapy and continue during radiation therapy.

How to use flutamide

Harder S, Staib AH, Beer C, et al. 4-quinolones inhibit biotransformation of caffeine. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. Geier M, Geier D 2005. "The potential importance of steroids in the treatment of autistic spectrum disorders and other disorders involving mercury toxicity". Med Hypotheses. Warnings: Children: Black tea is POSSIBLY SAFE when taken by mouth by children in amounts commonly found in foods. Pregnancy and breast-feeding: If you are pregnant or breast-feeding, drinking black tea in small amounts is POSSIBLY SAFE. Do not drink more than 3 cups a day of black tea. This amount of tea provides about 200 mg of caffeine. Consuming more than this amount during pregnancy is POSSIBLY UNSAFE and has been linked to an increased risk of miscarriage, increased risk of sudden infant death syndrome SIDS and other negative effects, including symptoms of caffeine withdrawal in newborns and lower birth weight. If you are breast-feeding, drinking more than 3 cups a day of black tea is POSSIBLY UNSAFE and might cause your baby to become more irritable and have more bowel movements. Anemia: Drinking black tea may make anemia worse in people with iron deficiency. Anxiety disorders: The caffeine in black tea might make these conditions worse.

Does flutamide interact with other medications

Parsons, W. D. and Neims, A. H. Effect of smoking on caffeine clearance. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Serum transaminase levels should be measured prior to starting treatment with flutamide. Flutamide is not recommended in patients whose ALT values exceed twice the upper limit of normal. Serum transaminase levels should then be measured monthly for the first 4 months of therapy, and periodically thereafter. Liver function tests also should be obtained at the first signs and symptoms suggestive of liver dysfunction, eg, nausea, vomiting, abdominal pain, fatigue, anorexia, "flu-like" symptoms, hyperbilirubinuria, jaundice, or right upper quadrant tenderness. If at any time a patient has jaundice, or their ALT rises above 2 times the upper limit of normal, flutamide should be immediately discontinued with close follow-up of liver function tests until resolution.



Flutamide ingredients

Hematopoietic System: anemia occurred in 6%, leukopenia in 3%, and thrombocytopenia in 1% of patients. Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist. Wang, X. and Yeung, J. H. Effects of the aqueous extract from Salvia miltiorrhiza Bunge on caffeine pharmacokinetics and liver microsomal CYP1A2 activity in humans and rats. Raaska K, Raitasuo V, Laitila J, Neuvonen PJ. Effect of caffeine-containing versus decaffeinated coffee on serum clozapine concentrations in hospitalised patients. Maron DJ, Lu GP, Cai NS, et al. Cholesterol-lowering effect of a theaflavin-enriched green tea extract: a randomized controlled trial. Hertog MGL, Sweetnam PM, Fehily AM, et al. Antioxidant flavonols and ischemic heart disease in a Welsh population of men: the Caerphilly Study. Jr. Reduced risk of esophageal cancer associated with green tea consumption. J Natl. In animal studies, flutamide demonstrates potent antiandrogenic effects. If the patient has clinically evident jaundice, in the absence of biopsy-confirmed liver metastases, EULEXIN flutamide should be discontinued. In clinically patients, if transaminases increase over 2-3 times the upper limit of normal, treatment should be discontinued. The hepatic injury is usually reversible after discontinuation of therapy, and in some patients, after dosage reduction. However, there have been reports of death following severe hepatic injury associated with use of flutamide. The risk of hepatotoxicity with flutamide treatment is far higher than with nilutamide or bicalutamide. Lower dosages of the drug appear to have a reduced but still significant risk. Liver function should be monitored regularly with during flutamide treatment. In addition, due to the high risk of serious hepatotoxicity, flutamide should not be used in the absence of a serious indication. Do not keep outdated medicine or medicine no longer needed. Shitrit, A. A case-control study of caffeine and methylxanthines in benign breast disease. James Leonard Gulley 2011. McAnulty, J. H. Caffeine and ventricular arrhythmias. An electrophysiological approach.



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Ellis, P. R. The effect of consuming instant black tea on postprandial plasma glucose and insulin concentrations in healthy humans. J Am Coll. Dews PB, Curtis GL, Hanford KJ, O'Brien CP. The frequency of caffeine withdrawal in a population-based survey and in a controlled, blinded pilot experiment. Reduced sperm counts were observed during a 6 week study of Flutamide monotherapy in normal human volunteers. Levy, M. and Zylber-Katz, E. Caffeine metabolism and coffee-attributed sleep disturbances. Al-Attas, O. S. Tea consumption and the prevalence of coronary heart disease in Saudi adults: results from a Saudi national study. Prev. Risk of facial flushing, particularly if used in conjunction with alcohol. 31 Avoidance of alcohol recommended if flushing occurs. Haller CA, Benowitz NL, Jacob P 3rd. Hemodynamic effects of ephedra-free weight-loss supplements in humans. Giri, A. K. Anticlastogenic effects of black tea World blend and its two active polyphenols theaflavins and thearubigins in vivo in Swiss albino mice. Flutamide capsules are for use only in men. This product has no indication for women and should not be used in this population, particularly for nonserious or non-life threatening conditions. Intended Use and Disclaimer: Should not be printed and given to patients. This information is intended to serve as a concise initial reference for health care professionals to use when discussing medications with a patient. You must ultimately rely on your own discretion, experience, and judgment in diagnosing, treating, and advising patients. Black tea contains caffeine. The body breaks down caffeine to get rid of it. Fluconazole Diflucan might decrease how quickly the body gets rid of caffeine. This could cause caffeine to stay in to body too long and increase the risk of side effects such as nervousness, anxiety, and insomnia. Beilin, L. J. Regular ingestion of black tea improves brachial artery vasodilator function. Clin. Anon. Drugs of choice for cancer. Treat Guide Med Lett. Feminization of the male rats also occurred at the two higher dose levels. risperidone



About flutamide

Sanderink GJ, Bournique B, Stevens J, et al. Involvement of human CYP1A isoenzymes in the metabolism and drug interactions of riluzole in vitro. Jones, K. Green tea monograph. Altern. Ferrari P, Castagnetti G, Ferrari G, Baisi B, Dotti A "Combination treatment versus LHRH alone in advanced prostatic cancer. Curhan GC, Willett WC, Speizer FE, Stamfer MJ. Beverage use and risk of kidney stones in women. Academic Press. 19 March 2001. money order estrace pharmacy uk estrace



Flutamide uses

Kelly WK, Scher HI "Prostate specific antigen decline after antiandrogen withdrawal: the flutamide withdrawal syndrome. Langguth, P. Influence of green and black tea on folic acid pharmacokinetics in healthy volunteers: potential risk of diminished folic acid bioavailability. Biopharm. The body breaks down clozapine Clozaril to get rid of it. The caffeine in black tea seems to decrease how quickly the body breaks down clozapine Clozaril. Taking black tea along with clozapine Clozaril can increase the effects and side effects of clozapine Clozaril. The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your not to work correctly. These are possible, but not always occur. Your doctor or can often prevent or manage interactions by changing how you use your medications or by close monitoring. Tondo, L. and Rudas, N. The course of a seasonal bipolar disorder influenced by caffeine. Hertog MG, Feskens EJ, Hollman PC, et al. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Check with your pharmacist about how to dispose of unused medicine. Madsen, M. R. Metabolic effects of caffeine ingestion and physical work in 75-year old citizens. A randomized, double-blind, placebo-controlled, cross-over study. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. American Academy of Pediatrics. The transfer of drugs and other chemicals into human milk. Yudkin, J. Tea consumption and cancer. Bhattacharya, S. Comparative study of antioxidant potential of tea with and without additives. Indian J Physiol Pharmacol. Leigh, E. Antioxidant activity of tea unaffected by milk. Stemmermann, G. N. Black tea consumption and cancer risk: a prospective study. buy aggrenox melbourne australia



Leeds, A R Black tea--helpful or harmful?

Hodgson JM, Croft KD, Mori TA, et al. Regular ingestion of tea does not inhibit in vivo lipid peroxidation in humans. In the UK and Ireland, leuprorelin is marketed by Takeda UK as Prostap SR one-month injection and Prostap 3 three-month injection. Erusalimsky, J. D. The effects of chronic tea intake on platelet activation and inflammation: a double-blind placebo controlled trial. Other: edema occurred in 4%, genitourinary and neuromuscular symptoms in 2%, and pulmonary symptoms in less than 1% of patients. Wuttke W, Jarry H, Feleder C, Moguilevsky J, Leonhardt S, Seong JY, Kim K 1996. Drink plenty of fluids as directed by your doctor to reduce your risk of losing too much body water. Nineteen cases of severe flutamide the active ingredient contained in Eulexin related hepatotoxicity were reported by the FDA in 1993. The flutamide related hepatitis developed 56 to 80 days after the beginning of therapy and was mainly cytolytic. Four of the cases involved massive hepatic necrosis with fatal outcomes. The mechanism of action was believed to be direct hepatotoxicity. Ganguly, D. K. Anti-ulcer effect of the hot water extract of black tea Camellia sinensis. J Ethnopharmacol. Ramon J, Denis L 5 June 2007.



Bara AI, Barley EA Caffeine for asthma

Hydroxyflutamide: about 6 hours after a single 250-mg dose. Patients should be informed that Flutamide capsules and the drug used for medical castration should be administered concomitantly, and that they should not interrupt their dosing or stop taking these medications without consulting their physician. May DC, Jarboe CH, VanBakel AB, Williams WM. Effects of cimetidine on caffeine disposition in smokers and nonsmokers. Khan, M. A. Testicular atrophy and impaired spermatogenesis in rats fed high levels of the methylxanthines caffeine, theobromine, or theophylline. Weathersbee PS, Olsen LK, Lodge JR. Caffeine and pregnancy. A retrospective survey. Do not take other medicines unless they have been discussed with your doctor. Your doctor may adjust the doses of your medications or monitor you carefully for side effects. Dews PB, O'Brien CP, Bergman J. Caffeine: behavioral effects of withdrawal and related issues. Louis J Denis; Keith Griffiths; Amir V Kaisary; Gerald P Murphy 1 March 1999. Your doctor may prescribe anti-diarrhea medication such as loperamide to control your symptoms. Tell your doctor immediately if you develop severe or persistent diarrhea or signs of dehydration such as dizziness, decreased amount of urine. Wilson, M. F. Effects of caffeine on vascular resistance, cardiac output and myocardial contractility in young men. generic topamax stool softener



Prescribing information for flutamide

Willett, W. C. Relation between intake of flavonoids and risk for coronary heart disease in male health professionals. Ann. Zhao, B. Protective effects of green tea polyphenols and their major component, --epigallocatechin-3-gallate EGCG on 6-hydroxydopamine-induced apoptosis in PC12 cells. Redox. Lung cancer. Green tea and black tea contain chemicals called phytoestrogens. Some research shows that men who get more phytoestrogens in their diet have a lower risk of developing lung cancer than men who do not get these chemicals. However other early research suggests that drinking black tea is not linked with a reduced risk of lung cancer and may even be linked with an increased risk. Srisuphan, W. and Bracken, M. B. Caffeine consumption during pregnancy and association with late spontaneous abortion. Following a single 250 mg dose of flutamide administered to subjects with chronic renal insufficiency, there appeared to be no correlation between creatinine clearance and either C max or AUC of flutamide. Renal impairment did not have an effect on the C max or AUC of the biologically active alpha-hydroxylated metabolite of flutamide. For patients with objective progression of disease and elevated serum PSA, consider temporarily withdrawing flutamide while continuing LHRH analog. Pradhan, S. N. Carcinogenicity of Camellia sinensis tea and some tannin-containing folk medicinal herbs administered subcutaneously in rats. J Natl. Patients with preexisting gynecomastia as a result of previous endocrine therapy with estrogens sustained no worsening of their gynecomastia and may have improved symptomatically. William B. Pratt 1994. online meloxicam malarone meloxicam



Flutamide Tablets in this leaflet

Blackledge G. Casodex mechanisms of action and opportunities for usage. Cancer. Beard, D. Acute caffeine ingestion fatalities: management issues. Vet. The body breaks down the caffeine in black tea to get rid of it. Birth control pills can decrease how quickly the body breaks down caffeine. Taking black tea along with birth control pills can cause jitteriness, headache, fast heartbeat, and other side effects. Patients should be informed that Eulexin Capsules and the drug used for medical castration should be administered concomitantly, and that they should not interrupt their dosing or stop taking these medications without consulting their physician. Regular assessment of serum Prostate Specific Antigen PSA may be helpful in monitoring the patient's response. If PSA levels rise significantly and consistently during Flutamide therapy the patient should be evaluated for clinical progression. For patients who have objective progression of disease together with an elevated PSA, a treatment-free period of antiandrogen while continuing the LHRH analogue may be considered. Watson JM, Jenkins EJ, Hamilton P, et al. Influence of caffeine on the frequency and perception of hypoglycemia in free-living patients with type 1 diabetes. Your doctor may prescribe anti- such as to control your symptoms. Conlisk, A. J. and Galuska, D. A. Is caffeine associated with bone mineral density in young adult women? Flutamide should be taken together with other medicines used for surgery. Do not stop taking these medicines without checking with your doctor first. Haqqi, T. M. Epigallocatechin-3-gallate inhibits interleukin-1beta-induced expression of nitric oxide synthase and production of nitric oxide in human chondrocytes: suppression of nuclear factor kappaB activation by degradation of the inhibitor of nuclear factor kappaB. Arthritis Rheum. Jackson SH, Barker SJ "Methemoglobinemia in a patient receiving flutamide. Stop taking flutamide and seek emergency medical attention if you experience an allergic reaction difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives. Take your Flutamide capsules as your doctor has prescribed. The usual dosing is 2 capsules every 8 hours. Engelhardt, U. H. Flavonoids and other polyphenols in consumer brews of tea and other caffeinated beverages. J Agric. Before you take Flutamide. vibramycin



What is flutamide

No information is available on the relationship of age to the effects of flutamide in geriatric patients. Musculoskeletal side effects including muscle cramps in up to 15% of patients have been reported. Flutamide capsules are contraindicated in patients who are hypersensitive to Flutamide or any component of this preparation. De Freitas, B. and Schwartz, G. Effects of caffeine in chronic psychiatric patients. The usual dose is one tablet three times daily. Friedman, G. D. Coffee, tea, and mortality. Ann. Kalow, W. Variability in caffeine metabolism. Tu YY, Tang AB, Watanabe N. The theaflavin monomers inhibit the cancer cells growth in vitro.



Side effects of flutamide

Kinlen, L. J. and McPherson, K. Pancreas cancer and coffee and tea consumption: a case-control study. Easy-to-use online tool to effectively manage and update a hospital's formulary and communicate the most current formulary information facility-wide. Feminization of the males also occurred at the two higher dose levels. Shukla, Y. and Taneja, P. Anticarcinogenic effect of black tea on pulmonary tumors in Swiss albino mice. Cancer Lett. Leson CL, McGuigan MA, Bryson SM. Caffeine overdose in an adolescent male. National Library of Medicine and Drugs. Robelin, M. and Rogers, P. J. Mood and psychomotor performance effects of the first, but not of subsequent, cup-of-coffee equivalent doses of caffeine consumed after overnight caffeine abstinence. Behav. Taylor, D. R. Effect of caffeine ingestion on exhaled nitric oxide measurements in patients with asthma. should i prometrium



Reviews for flutamide

Ascherio A, Zhang SM, Hernan MA, et al. Prospective study of caffeine intake and risk of Parkinson's disease in men and women. Proceedings 125th Ann Mtg Am Neurological Assn. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate. Hashim, H. and Al, Mousa R. Management of fluid intake in patients with overactive bladder. Curr. Geleijnse JM, Launer LJ, van der Kuip DA, et al. Inverse association of tea and flavonoid intakes with incident myocardial infarction: the Rotterdam Study. Hematologic side effects have included anemia 6% leukopenia 3% and thrombocytopenia 1%. Flutamide has also been implicated in cases of methemoglobinemia, sulphemoglobinemia and neutropenia. In addition, eosinophilia has been reported in association with some cases of hepatotoxicity. Malignant breast neoplasms have occurred rarely in male patients being treated with Flutamide. Kennealey GT, Furr BJA. Use of the nonsteroidal anti-androgen Casodex in advanced prostatic carcinoma. Rush University Medical Center. Sarkar, A. and Bhaduri, A. Black tea is a powerful chemopreventor of reactive oxygen and nitrogen species: comparison with its individual catechin constituents and green tea. Biochem. Leenen R, Roodenburg AJ, Tijburg LB, et al. A single dose of tea with or without milk increases plasma antioxidant activity in humans. Migliardi JR, Armellino JJ, Friedman M, et al. Caffeine as an analgesic adjuvant in tension headache. zepzip.info losartan



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It is very important that your doctor check your progress at regular visits to make sure that flutamide is working properly. Blood tests may be needed to check for unwanted effects. If you get any side effects talk to your doctor or pharmacist. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Following a single 250 mg dose of Flutamide administered to subjects with chronic renal insufficiency, there appeared to be no correlation between creatinine clearance and either C max or AUC of Flutamide. Renal impairment did not have an effect on the C max or AUC of the biologically active alpha-hydroxylated metabolite of Flutamide. Lane JD, Barkauskas CE, Surwit RS, Feinglos MN. Caffeine impairs glucose metabolism in type 2 diabetes. The effects of combination therapy have been evaluated in two studies. One study evaluated the effects of flutamide and an LHRH-agonist as neoadjuvant therapy to radiation in stage B 2-C prostatic carcinoma and the other study evaluated flutamide and an LHRH-agonist as the sole therapy in stage D 2 prostatic carcinoma. Lake CR, Rosenberg DB, Gallant S, et al. Phenylpropanolamine increases plasma caffeine levels. imuran



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General information about flutamide


What are the side effects of desipramine?

The recommended dosage of Eulexin is 2 capsules, 3 times a day at 8-hour intervals. Warfarin may interact with Eulexin. Before taking Eulexin your doctor will monitor your liver function. Eulexin is not indicated for women of child bearing age, therefore you should not take Eulexin if you are pregnant or breastfeeding. Warfarin Coumadin is used to slow blood clotting. Large amounts of black tea might decrease how well warfarin Coumadin slows blood clotting. Decreasing the how well warfarin Coumadin slows blood clotting might increase the risk of clotting. It is unclear why this interaction might occur. Be sure to have your blood checked regularly. The dose of your warfarin Coumadin might need to be changed. best price for doxazosin 100mg

Before taking flutamide

Croft, K. D. Gallic acid metabolites are markers of black tea intake in humans. J Agric. Serum transaminase levels should be measured prior to starting treatment with flutamide. Flutamide is not recommended in patients whose ALT values exceed twice the upper limit of normal. Serum transaminase levels should then be measured monthly for the first 4 months of therapy, and periodically thereafter. Liver function tests also should be obtained at the first signs and symptoms suggestive of liver dysfunction eg, nausea, vomiting, abdominal pain, fatigue, anorexia, “flu-like” symptoms, hyperbilirubinuria, jaundice, right upper quadrant tenderness. If at any time, a patient has jaundice, or their ALT rises above 2 times the upper limit of normal, flutamide should be immediately discontinued with close follow-up of liver function tests until resolution. purchase dramamine legally online

Yudkin, J Tea consumption and cancer

Store flutamide at room temperature, 59 to 86 degrees F 15 to 30 degrees C in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep flutamide out of the reach of children and away from pets. Vanhanen, L. Bioavailability of soluble oxalate from tea and the effect of consuming milk with the tea. Eur. Cronin JR. Green tea extract stokes thermogenesis: will it replace ephedra? Watson JM, Sherwin RS, Deary IJ, et al. Dissociation of augmented physiological, hormonal and cognitive responses to hypoglycaemia with sustained caffeine use.

Lutz Moser 1 January 2008

Cardiovascular System: hypertension in 1% of patients. Schott AM, Vial T, Gozzo I, Chareyre S, Delmas PD "Flutamide-induced methemoglobinemia. The effects of combination therapy have been evaluated in two studies. One study evaluated the effects of flutamide and an as neoadjuvant therapy to in B 2-C prostatic carcinoma and the other study evaluated flutamide and an LHRH as the sole therapy in stage D 2 metastatic carcinoma. Leuprorelin acts as an agonist at receptors. By interrupting the normal pulsatile stimulation of, and thus desensitizing, the GnRH receptors, it indirectly downregulates the secretion of gonadotropins LH and FSH leading to and thus a dramatic reduction in and levels in both sexes.

AST and ALT occasionally occurred. The body breaks down the caffeine in black tea to get rid of it. Alcohol can decrease how quickly the body breaks down caffeine. Taking black tea along with alcohol might cause too much caffeine in the bloodstream and caffeine side effects including jitteriness, headache, and fast heartbeat. Wysowski DK, Fourcroy JL "Hepatotoxicity complicating flutamide treatment of hirsutism - reply. Analysis of plasma, urine, and feces following a single oral 200 mg dose of tritium-labeled flutamide to human volunteers showed that the drug is rapidly and completely absorbed. Following a single 250 mg oral dose to normal adult volunteers, the biologically active alpha-hydroxylated metabolite reaches maximum plasma concentrations in about 2 hours, indicating that it is rapidly formed from flutamide. Food has no effect on the bioavailability of flutamide.

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